Associate Scientist - Cell Engineering
: Job Details :


Company : Abcam


Job Location : Cambridge, Cambridgeshire, UK


Posted on : 2021-04-04T09:34:13Z


Job Description :

About the role:

The Abcam Cell Engineering Team is looking for an associate scientist. This is an exciting opportunity to join a rapidly growing group focused on generating a large collection of physiologically relevant cellular models.

Role & Responsibilities:

In this role, you will use cutting edge technologies and CRISPR/ genome editing to endogenously modify and characterise a variety of cell lines i.e. cancer cells, mammalian or primary cells, immune and neurones cells. As part of the Technology Development department you will work within a multifaceted community with broad technical expertise to improve current gene editing techniques. This laboratory-based role will give you the opportunity to apply molecular and cell biology expertise; obtain practical experience in launching large pipeline of cellular models; build expertise in multiple research areas i.e. Neuroscience, Epigenetics, Immunology-oncology and Cardiovascular metabolism; and finally collaboratively work across many business areas with local and global matrix teams.

About you:

In this role, you will use cutting edge technologies and CRISPR/ genome editing to endogenously modify and characterise a variety of cell lines i.e. cancer cells, mammalian or primary cells, immune and neurones cells. As part of the Technology Development department you will work within a multifaceted community with broad technical expertise to improve current gene editing techniques. This laboratory-based role will give you the opportunity to apply molecular and cell biology expertise; obtain practical experience in launching large pipeline of cellular models; build expertise in multiple research areas i.e. Neuroscience, Epigenetics, Immunology-oncology and Cardiovascular metabolism; and finally collaboratively work across many business areas with local and global matrix teams.

Essential Requirements:
  • MSc in Biology or a related discipline
  • Experience with CRISPR/Cas9 genome editing
  • Experience in CRISPR reagent delivery : lipofection/ electroporation
  • DNA extraction and Genotyping
  • Single cell Cloning : FACS, limiting dilution or other technologies
  • Hands-on experience with various cellular models: cancer, immune and primary cells, neurones etc
  • Strong experimental design and problem-solving skills
  • Excellent team working, communication and networking skills with experience of interacting effectively across interfaces of discipline, culture, and expertise. Desirable Requirements:
    • Ph.D in Biology or a related discipline
    • Experience with d esigning and implementing focused or genome-wide CRISPR screen
    • Developing and running phenotypic assays such as cellular imaging and FACS
    • Experience of cell-based assays and high content imaging
    • Experience in NGS and NGS data analysis
    • Experience of Mass Spectrometry If this sounds like you and you'd like to be a part of a fast paced, growing business with the vision to become the most influential company and best-loved brand in life sciences please apply now!

      Pay and Benefits

      In addition to competitive salaries, we offer an attractive and flexible benefits package (including our award-winning share scheme, 18 weeks full paid maternity leave and 6 weeks full paid paternity leave), a culture focused on well-being and opportunities for growth and development, and a highly flexible working environment.

      What's more, as a WORK180 Endorsed Employer, we are recognized globally as an organization that's diverse, inclusive and supports women in the workplace.

      About Us

      An idea conceived in a University of Cambridge laboratory in 1998, Abcam plc (www.abcamplc.com) began life as an innovative and entrepreneurial start-up, spearheaded by like-minded individuals who shared a common purpose of providing the scientific community with quality antibody reagents, as well as trustworthy and up-to-date information about their uses and limitations. Abcam has now grown to become a leading supplier of protein research tools to life scientists, whilst always maintaining the core collaborative values assumed at its inception.

      Abcam now supports life science researchers in their quest to understand the cause of disease and ultimately offer improvements to diagnoses and treatments. To achieve this outcome, the company both develops and manufactures its own products in specialist facilities across the globe, and sources from over 400 partners, offering scientists the newest, most innovative and highest quality research tools available globally, regardless of source. With a customer base of research scientists who require high performance products with detailed technical specifications, 64% of global researchers use Abcam products.

      Inclusion & Diversity

      Abcam is an Equal Opportunity Employer and makes all employment decisions without regard to age, national origin, race, ethnicity, religion, creed, gender, sexual orientation, disability, veteran status, or any other characteristic protected by law.



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